| Date | IP Address |
| 2021-11-29 | 23.209.37.83 (ClassC) |
| 2023-12-01 | 23.48.104.13 (ClassC) |
| 2024-12-12 | 23.44.175.148 (ClassC) |
| 2025-02-23 | 23.46.228.172 (ClassC) |
| 2025-03-15 | 23.46.228.174 (ClassC) |
| 2025-08-05 | 23.59.88.44 (ClassC) |
| 2025-12-06 | 184.25.123.20 (ClassC) |
| 2025-12-24 | 23.216.147.198 (ClassC) |
| 2026-02-01 | 23.216.147.206 (ClassC) |
| Date | Domain | IP |
| email.mail.xerispharma.com | 2025-12-24 | 34.110.180.34 |
| ir.xerispharma.com | 2024-12-12 | 23.44.175.148 |
| investors.xerispharma.com | 2024-09-19 | 104.98.114.194 |
| www.xerispharma.com | 2023-12-23 | 184.28.93.11 |