| Date | IP Address |
| 2024-08-25 | 173.237.160.161 (ClassC) |
| 2026-02-06 | 3.141.146.16 (ClassC) |
| Date | Domain | IP |
| image.hcp-ca.apellis.com | 2025-10-21 | 23.192.230.133 |
| pi.apellis.com | 2026-01-02 | 3.141.146.16 |
| autodiscover.apellis.com | 2024-07-10 | 52.96.91.56 |
| investors.apellis.com | 2024-02-22 | 104.96.163.197 |
| image.health-us.apellis.com | 2025-04-19 | 23.192.230.134 |
| image.ecp-us.apellis.com | 2025-04-19 | 23.192.230.134 |
| image.hcp-au.apellis.com | 2025-10-06 | 23.192.230.153 |
| www.apellis.com | 2025-12-31 | 3.141.146.16 |