| Date | IP Address |
| 2019-04-01 | 40.97.131.120 (ClassC) |
| 2024-07-10 | 52.96.91.56 (ClassC) |
| 2024-09-04 | 52.96.165.72 (ClassC) |
| 2025-02-11 | 52.96.166.248 (ClassC) |
| 2025-03-07 | 52.96.166.40 (ClassC) |
| 2025-04-23 | 52.96.17.8 (ClassC) |
| 2025-04-27 | 52.96.113.216 (ClassC) |
| 2025-08-01 | 52.96.223.56 (ClassC) |
| Date | Domain | IP |
| pi.apellis.com | 2025-04-21 | 3.141.146.16 |
| autodiscover.apellis.com | 2024-07-10 | 52.96.91.56 |
| investors.apellis.com | 2024-02-22 | 104.96.163.197 |
| image.health-us.apellis.com | 2025-04-19 | 23.192.230.134 |
| image.ecp-us.apellis.com | 2025-02-13 | 23.192.230.156 |
| image.hcp-au.apellis.com | 2025-07-30 | 23.192.230.133 |
| www.apellis.com | 2025-06-26 | 3.141.146.16 |