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HTTP/1.1 200 OKContent-Type: text/html; charsetutf-8Date: Mon, 21 Oct 2024 16:34:45 GMTServer: Microsoft-IIS/10.0Set-Cookie: ARRAffinityccaf055fd1d84a43121b3f98a62b3ed0a4a8fa41d2e6f072230136cc936ff633;Path/;HttpOnly;Secure;Domainwww.xtandi.comSet-Cookie: ARRAffinitySameSiteccaf055fd1d84a43121b3f98a62b3ed0a4a8fa41d2e6f072230136cc936ff633;Path/;HttpOnly;SameSiteNone;Secure;Domainwww.xtandi.comTransfer-Encoding: chunkedStrict-Transport-Security: max-age2592000X-Powered-By: ASP.NET !DOCTYPE html>html langen classno-js home>head> !-- OneTrust Cookies Consent Notice start for www.xtandi.com --> script srchttps://cdn.cookielaw.org/scripttemplates/otSDKStub.js typetext/javascript charsetUTF-8 data-domain-script018fbe8f-b316-72b5-aa78-ae71214fd1b1 >/script> script typetext/javascript> function OptanonWrapper() { } /script> !-- OneTrust Cookies Consent Notice end for www.xtandi.com --> meta charsetutf-8 /> meta nameviewport contentwidthdevice-width, initial-scale1, minimum-scale1, shrink-to-fitno> title>XTANDI® (enzalutamide) | Advanced Prostate Cancer Treatment/title> meta namegoogle-site-verification contentARzbWVkqhYMZxrETweQtWXFts8TD9relTM6KFoepmjU /> meta namedescription contentXTANDI® is an androgen receptor inhibitor (ARI) used for the treatment of four types of advanced prostate cancer, including mCRPC, nmCRPC, mCSPC, and nmCSPC with high risk of cancer spreading. See Important Safety Information, Risks, and Benefits.> meta namerobots contentindex, follow> link relcanonical hrefhttps://www.xtandi.com/ /> meta propertyog:title contentXTANDI® (enzalutamide) /> meta propertyog:description contentLearn more about XTANDI® (enzalutamide). /> meta propertyog:url contenthttps://www.xtandi.com/ /> meta propertyog:image contenthttps://www.xtandi.com/images/og-xtandi-logo.jpg /> meta propertyog:image:width content1200> meta propertyog:image:height content630> meta propertyog:type contentwebsite /> meta propertyog:site_name contentXTANDI /> meta propertyfb:app_id content4190091207733588> link relapple-touch-icon sizes180x180 href/apple-touch-icon.png> link relicon typeimage/png sizes32x32 href/favicon-32x32.png> link relicon typeimage/png sizes16x16 href/favicon-16x16.png> link relmanifest href/site.webmanifest> link relmask-icon href/safari-pinned-tab.svg color#bf3119> meta namemsapplication-TileColor content#ffffff> meta nametheme-color content#ffffff> script> document.documentElement.classList.replace(no-js, js); /script> !-- Google Tag Manager --> script>(function(w,d,s,l,i){wlwl||;wl.push({gtm.start: new Date().getTime(),event:gtm.js});var fd.getElementsByTagName(s)0, jd.createElement(s),dll!dataLayer?&l+l:;j.asynctrue;j.src https://www.googletagmanager.com/gtm.js?id+i+dl;f.parentNode.insertBefore(j,f); })(window,document,script,dataLayer,GTM-NCNFB8);/script> !-- End Google Tag Manager --> script typeapplication/ld+json> {@context: http://schema.org, @type: MedicalWebPage, audience: https://schema.org/Patient, specialty: https://schema.org/Oncologic, url: https://www.xtandi.com/, name: XTANDI® (enzalutamide) | Advanced Prostate Cancer Treatment, headline: #1 prescribed androgen receptor inhibitor (ARI)*, description: XTANDI® is an androgen receptor inhibitor (ARI) used for the treatment of four types of advanced prostate cancer, including mCRPC, nmCRPC, mCSPC, and nmCSPC with rapidly rising PSA. See Important Safety Information, Risks, and Benefits., potentialAction: {@type: Action, name: Learn more, description: Savings & Support: Find out more information about financial support options that may help eligible patients., url: https://www.xtandi.com/financial-support}, {@type: Action, name: Watch their stories, description: Gain perspective into the lives of men living with advanced prostate cancer and taking XTANDI., url: https://www.xtandi.com/patient-videos}, {@type: Action, name: Watch story, description: The Power of Support, url: https://www.xtandi.com/patient-videos/power-of-support}, {@type: Action, name: Watch story, description: Self-Advocating, url: https://www.xtandi.com/patient-videos/self-advocating}, {@type: Action, name: Watch story, description: Journey to Access, url: https://www.xtandi.com/patient-videos/journey-to-access}, {@type: Action, name: Watch story, description: Advice, url: https://www.xtandi.com/patient-videos/advice}, {@type: Action, name: Watch story, description: Treatment, url: https://www.xtandi.com/patient-videos/treatment}, {@type: Action, name: Learn more, description: Select Safety Information, url: https://www.xtandi.com/side-effects}, {@type: Action, name: Sign up, description: Sign up for support emails and resources, url: https://www.xtandi.com/support-sign-up}, about: { @type: Drug, name: XTANDI, nonProprietaryName: enzalutamide, image: {@type: ImageObject, name: XTANDI® (enzalutamide) 40 mg tablets | 80 mg tablets, description: XTANDI Logo, contentUrl: https://www.xtandi.com/images/logo-xtandi.svg}, description: What is XTANDI? XTANDI is a prescription medicine used to treat men with prostate cancer that: no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone OR has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body. It is not known if XTANDI is safe and effective in females or children., prescribingInfo: https://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf, warning: What should I tell my doctor before taking XTANDI? Tell your doctor about all your medical conditions, including if you: Have a history of seizures, brain injury, stroke, or brain tumors. Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant. Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose. Males must use a condom during sex with a pregnant female. Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk. Take other medicines. XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor. How should I take XTANDI? Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed. Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first. If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration). If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day. If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI. What are the possible side effects of XTANDI? XTANDI may cause serious side effects including: Seizure. If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure. Posterior Reversible Encephalopathy Syndrome (PRES). If you take XTANDI you may be at risk of developing a condition involving the brain called PRES. Tell your doctor right away if you have a seizure or quickly worsening symptoms such as headache, decreased alertness, confusion, reduced eyesight, blurred vision or other visual problems. Your doctor will do a test to check for PRES. Allergic Reactions. Allergic reactions have happened in people who take XTANDI. Stop taking XTANDI and get medical help right away if you develop swelling of the face, tongue, lip or throat. Heart Disease. Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment. Call your doctor or go to the emergency room right away if you get chest pain or discomfort at rest or with activity or shortness of breath during your treatment with XTANDI. Falls and Bone Fractures. XTANDI treatment may increase your risk for falls and bone fractures. Falls were not caused by loss of consciousness or seizures. Your doctor will monitor your risks for falls and bone fractures during treatment with XTANDI. Your doctor will stop treatment with XTANDI if you have serious side effects. The most common side effects of XTANDI include: Muscle and joint pain Feeling more tired than usual Hot flashes Constipation Decreased appetite Diarrhea High blood pressure Bleeding problems Falls Bone fractures Headache XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility. These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. For further information, please talk to your doctor and click here for Patient Information and Full Prescribing Information for XTANDI., prescriptionStatus: https://health-lifesci.schema.org/PrescriptionOnly, dosageForm: tablets, administrationRoute: oral, doseSchedule: {@type: DoseSchedule, frequency: XTANDI is taken by mouth and is available in 2 dosage strengths: 40 mg and 80 mg. Take XTANDI once a day, at the same time every day, with or without food.}, offers: { @type: Offer, price: 0, priceCurrency: USD, url: https://www.xtandi.com/}, manufacturer: {@type: Organization, name: Astellas, logo: https://www.xtandi.com/img/logo-astellas.png}}}/script> link relstylesheet typetext/css href/styles/base.css?vHgHZSyG3PC-FLYS71beZtfDjwmugHeRPVUE6ETZVZv8 /> link relstylesheet typetext/css href/styles/home.css /> script defer typetext/javascript src/scripts/runtime.bundle.min.js?vs1N2tBpgfiIFfRsiqvpAnPUMvEAg5NLdyNOo_nmq7c4>/script> script defer typetext/javascript src/scripts/base.bundle.min.js?v-LA-U6s3BoSZC_wu-aZpVPND0aJeyF9ULQxW9eCcya8>/script> script defer typetext/javascript src/scripts/home.bundle.min.js>/script>/head>body> !-- Google Tag Manager (noscript) --> noscript>iframe srchttps://www.googletagmanager.com/ns.html?idGTM-NCNFB8 height0 width0 styledisplay:none;visibility:hidden>/iframe>/noscript> !-- End Google Tag Manager (noscript) --> div classouter-container> !-- Modal for Healthcare Professionals-->div classmodal fade idpopUp1 aria-labelledbypopUp1Label aria-hiddentrue> div classmodal-dialog modal-dialog-centered tabindex-1> div classmodal-content> div classmodal-header> h4 classmodal-title fs-5 idpopUp1Label>You are now leaving XTANDI.com/h4> button typebutton classbtn-close data-bs-dismissmodal aria-labelClose>/button> /div> div classmodal-body> p>Please verify that you are a U.S. Healthcare Professional./p> p>This information is intended for U.S. Healthcare Professionals only./p> h4>Are you a U.S. Healthcare Professional?/h4> /div> div classmodal-footer> button typebutton classcta-btn cta-btn-primary cta-popup data-bs-dismissmodal>No/button> a href# target_blank classcta-btn cta-btn-primary cta-popup wt-yes-button>Yes/a> /div> /div> /div>/div> !-- Modal -->div classmodal fade idpopUp2 aria-labelledbypopUp2Label aria-hiddentrue> div classmodal-dialog modal-dialog-centered tabindex-1> div classmodal-content> div classmodal-header> h4 classmodal-title fs-5 idpopUp2Label>You are now leaving XTANDI.com/h4> button typebutton classbtn-close data-bs-dismissmodal aria-labelClose>/button> /div> div classmodal-body> p>The website you are about to visit is not owned or controlled by Astellas or Pfizer. Astellas and Pfizer are not responsible for the information or services on this site./p> /div> div classmodal-footer> button typebutton classcta-btn cta-btn-primary data-bs-dismissmodal>Cancel/button> a href# target_blank classcta-btn cta-btn-primary wt-yes-button>Continue/a> /div> /div> /div>/div> header classheader> aside classindication-popup with-grid collapse show idindicationPopup> div classindication-popup__inner-container with-grid> div classcell-1> a classdownload-link-ip hrefhttps://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf target_blank> i classdownload-link-ip__icon> svg idb xmlnshttp://www.w3.org/2000/svg viewBox0 0 11.56 16>g idc>g idd>path dm11.07,8.26l-4.34,3.64c-.19.18-.42.29-.67.34,0,0,0,0,0,0-.01,0-.02,0-.03,0,0,0,0,0,0,0,0,0-.02,0-.02,0,0,0,0,0-.01,0,0,0-.01,0-.02,0,0,0,0,0-.01,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0h-.03s-.01,0-.02,0c0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0,0,0-.01,0,0,0-.01,0-.02,0,0,0,0,0-.01,0,0,0-.02,0-.02,0,0,0,0,0,0,0-.01,0-.02,0-.03,0,0,0,0,0,0,0-.25-.05-.48-.17-.67-.34L.49,8.26c-.58-.49-.66-1.36-.17-1.95.49-.58,1.36-.66,1.95-.17l2.03,1.7V1.48c0-.81.67-1.48,1.48-1.48s1.48.67,1.48,1.48v6.37l2.03-1.7c.58-.49,1.46-.41,1.95.17.49.58.41,1.46-.17,1.95h0Z fill#fff/>path dm10.35,13.57c.67,0,1.21.54,1.21,1.21s-.54,1.21-1.21,1.21H1.21c-.67,0-1.21-.54-1.21-1.21s.54-1.21,1.21-1.21h9.13Z fill#fff/>/g>/g>/svg> /i> span classdownload-link-ip__label>Prescribing Information/span> /a> a classdownload-link-ip hrefhttps://www.astellas.us/docs/us/12A005-ENZ-Patient%20Package%20Insert-WPI.pdf target_blank> i classdownload-link-ip__icon> svg idb xmlnshttp://www.w3.org/2000/svg viewBox0 0 11.56 16>g idc>g idd>path dm11.07,8.26l-4.34,3.64c-.19.18-.42.29-.67.34,0,0,0,0,0,0-.01,0-.02,0-.03,0,0,0,0,0,0,0,0,0-.02,0-.02,0,0,0,0,0-.01,0,0,0-.01,0-.02,0,0,0,0,0-.01,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0h-.03s-.01,0-.02,0c0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0-.01,0-.02,0,0,0,0,0-.01,0,0,0-.01,0-.02,0,0,0,0,0-.01,0,0,0-.02,0-.02,0,0,0,0,0,0,0-.01,0-.02,0-.03,0,0,0,0,0,0,0-.25-.05-.48-.17-.67-.34L.49,8.26c-.58-.49-.66-1.36-.17-1.95.49-.58,1.36-.66,1.95-.17l2.03,1.7V1.48c0-.81.67-1.48,1.48-1.48s1.48.67,1.48,1.48v6.37l2.03-1.7c.58-.49,1.46-.41,1.95.17.49.58.41,1.46-.17,1.95h0Z fill#fff/>path dm10.35,13.57c.67,0,1.21.54,1.21,1.21s-.54,1.21-1.21,1.21H1.21c-.67,0-1.21-.54-1.21-1.21s.54-1.21,1.21-1.21h9.13Z fill#fff/>/g>/g>/svg> /i> span classdownload-link-ip__label>Patient Information/span> /a> /div> div classcell-2> button classindication-popup__close-btn typebutton data-bs-togglecollapse data-bs-target#indicationPopup aria-expandedtrue aria-controlsindicationPopup aria-labelClose>/button> p>XTANDI (enzalutamide) is a prescription medicine used to treat men with prostate cancer that:/p> ul classindication-popup__list> li>no longer responds to a hormone therapy or surgical treatment to lower testosterone OR/li> li>has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone OR/li> li>has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body/li> /ul> p>It is not known if XTANDI is safe and effective in females or children./p> /div> /div>/aside> div classprimary-nav with-grid> nav classprimary-nav__nav navbar navbar-expand-lg> div classprimary-nav__wrapper with-grid> a href/ aria-labelGo to Homepage> img roleimg classlogo src/images/logo-xtandi.svg altXTANDI® (enzalutamide) 40 mg tablets | 80 mg tablets> /a> button classbtn-hamburger collapsed typebutton data-bs-togglecollapse data-bs-target#mainNavbarCollapse aria-controlsmainNavbarCollapse aria-expandedfalse aria-labelToggle main navigation>/button> /div> div idmainNavbarCollapse classprimary-nav__navbar-collapse collapse navbar-collapse> div classprimary-nav__container-scroll> div classaccess-support-call access-support-call--mobile-only> p>For Access Support call 1-855-898-2634/p> /div> ul classprimary-nav__list> li classprimary-nav__list-item> button classnav-section-btn dropdown-toggle typebutton data-bs-toggledropdown data-bs-auto-closefalse aria-expandedfalse> span classlabel>About XTANDI/span> /button> nav idaboutXtandi classsubnav dropdown-menu> ul classsubnav__list> li classsubnav__item subnav__item--with-icon> a classsubnav__link href/clinical-trials> i classsubnav__link-icon aria-hiddentrue>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-clinical-results>/use>/svg>/i> span classsubnav__link-label>Clinical results/span> /a> /li> li classsubnav__item subnav__item--with-icon> a classsubnav__link href/side-effects> i classsubnav__link-icon aria-hiddentrue>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-side-effects>/use>/svg>/i> span classsubnav__link-label>Side effects/span> /a> /li> li classsubnav__item subnav__item--bottom-flow> a classsubnav__link href/how-xtandi-works> span classsubnav__link-label>How XTANDI works/span> /a> /li> li classsubnav__item subnav__item--bottom-flow> a classsubnav__link href/understanding-prostate-cancer> span classsubnav__link-label>Different types of prostate cancer/span> /a> /li> li classsubnav__item subnav__item--bottom-flow> a classsubnav__link href/asking-about-xtandi> span classsubnav__link-label>When to ask your doctor about XTANDI/span> /a> /li> /ul> div classaccess-support-call access-support-call--desktop-only> p>For Access Support call 1-855-898-2634/p> /div> /nav> /li> li classprimary-nav__list-item> button classnav-section-btn dropdown-toggle typebutton data-bs-toggledropdown data-bs-auto-closefalse aria-expandedfalse> span classlabel>Starting XTANDI/span> /button> nav idstartingXtandi classsubnav dropdown-menu> ul classsubnav__list> li classsubnav__item subnav__item--with-icon> a classsubnav__link href/starting-treatment> i classsubnav__link-icon aria-hiddentrue>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-how-to-get-xtandi>/use>/svg>/i> span classsubnav__link-label>Getting XTANDI/span> /a> /li> li classsubnav__item subnav__item--with-icon> a classsubnav__link href/how-to-take> i classsubnav__link-icon aria-hiddentrue>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-taking-xtandi>/use>/svg>/i> span classsubnav__link-label>Taking XTANDI/span> /a> /li> /ul> div classaccess-support-call access-support-call--desktop-only> p>For Access Support call 1-855-898-2634/p> /div> /nav> /li> li classprimary-nav__list-item> a href/financial-support classnav-section-btn nav-section-btn--no-icon > span classlabel>Savings & Support/span> /a> /li> li classprimary-nav__list-item> button classnav-section-btn dropdown-toggle typebutton data-bs-toggledropdown data-bs-auto-closefalse aria-expandedfalse> span classlabel>Patient Stories & Resources/span> /button> nav idpatientStories classsubnav dropdown-menu> ul classsubnav__list> li classsubnav__item subnav__item--with-icon> a classsubnav__link href/patient-videos> i classsubnav__link-icon aria-hiddentrue>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-real-people-real-stories>/use>/svg>/i> span classsubnav__link-label>Real patient stories/span> /a> /li> li classsubnav__item subnav__item--with-icon> a classsubnav__link href/patient-resources> i classsubnav__link-icon aria-hiddentrue>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-patient-resources>/use>/svg>/i> span classsubnav__link-label>Resource hub/span> /a> /li> li classsubnav__item subnav__item--bottom-column-1> a classsubnav__link href/talking-to-your-doctor> span classsubnav__link-label>Doctor discussion guide/span> /a> /li> li classsubnav__item subnav__item--bottom-column-2> a classsubnav__link href/clinical-glossary> span classsubnav__link-label>Clinical glossary/span> /a> /li> li classsubnav__item subnav__item--bottom-column-3> a classsubnav__link href/faqs> span classsubnav__link-label>FAQs/span> /a> /li> li classsubnav__item subnav__item--bottom-column-1> a classsubnav__link href/staying-on-track> span classsubnav__link-label>Tips for staying on track/span> /a> /li> li classsubnav__item subnav__item--bottom-column-2> a classsubnav__link href/support-sign-up> span classsubnav__link-label>Sign up for support/span> /a> /li> li classsubnav__item subnav__item--bottom-column-3> a classsubnav__link href/downloadable-resources> span classsubnav__link-label>Downloadable resources/span> /a> /li> /ul> div classaccess-support-call access-support-call--desktop-only> p>For Access Support call 1-855-898-2634/p> /div> /nav> /li> /ul> /div> /div> /nav>/div> nav classutility-nav with-grid> ul classutility-nav__innner-container> li classutility-nav__item> a classutility-nav__link href#isiPanel data-isi-toggletrue> Important Safety Information /a> /li> li classutility-nav__item> a classutility-nav__link hrefhttps://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf target_blank>Prescribing Information/a> /li> li classutility-nav__item> a classutility-nav__link hrefhttps://www.astellas.us/docs/us/12A005-ENZ-Patient%20Package%20Insert-WPI.pdf target_blank>Patient Information/a> /li> li classutility-nav__item> a classutility-nav__link data-bs-togglecollapse href#indicationPopup rolebutton aria-expandedtrue aria-controlsindicationPopup> Indications /a> /li> li classutility-nav__item> a href# classutility-nav__link utility-nav__link--highlighted wt-open-modal data-bs-togglemodal data-bs-target#popUp1 data-urlhttps://www.xtandihcp.com/ data-labelHealthcare Professionals>For Healthcare Professionals/a> /li> /ul>/nav> div classbackdrop>/div>/header> main classouter-container rolemain> section classhero-banner-home with-grid> div classwhite-box> h1 classh1>#1 prescribed androgen receptor inhibitor (ARI)sup>a href#note1>*/a>/sup>/h1> a href/clinical-trials classcta-btn cta-btn-primary>See clinical results/a> div classhero-banner-home__footnote> p idnote1 classts-footnote>sup classts-footnote__asterisk>*/sup>A class of prostate cancer drugs that decreases how often androgens like testosterone connect with an androgen receptor./p> p classts-footnote>span classts-footnote__subtext>Source: IQVIA market data of TRx volume for CRPC and mCSPC for all branded prostate cancer medications, Jan-Jul 2023/span>/p> p classts-footnote>span classts-footnote__subtext>THIS INFORMATION DOES NOT IMPLY SAFETY OR EFFICACY OF ANY PRODUCT. NO COMPARISONS SHOULD BE MADE./span>/p> /div> /div> picture> source srcset/images/home-hero-banner-large.jpg media(min-width: 2000px) /> source srcset/images/home-hero-banner-desktop.jpg media(min-width: 992px) /> img roleimg classhero-banner-home__bg src/images/home-hero-banner-mobile.jpg altXTANDI patient Reggie holding a camera. /> /picture>/section>section classfinancial-support with-grid> div classfinancial-support__inner-container with-grid> div classcell-1> h2 classfinancial-support__title h1>Savings & support/h2> p classfinancial-support__info ts-paragraph-big>Find out more information about financial support options that may help eligible patients./p> p classfinancial-support__elegibility ts-footnote>Subject to eligibility. Void where prohibited by law./p> a href/financial-support classcta-btn cta-btn-secondary>Learn more/a> /div> div classcell-2 > img classfinancial-support__icon src/images/icon-financial-support.svg alt> /div> /div>/section>section classreal-patient-stories with-grid> h2 classreal-patient-stories__title h1>Real patient stories/h2> p classreal-patient-stories__subtitle>Gain perspective into the lives of men living with advanced prostate cancer and taking XTANDI./p> article classsplide real-patient-stories__carousel idrealPatientStoriesCarousel> div classsplide__track> ul classsplide__list> li classsplide__slide is-current> div classreal-patient-stories__slide story-1> div classreal-patient-stories__image-container> picture> source srcset/images/home-slider/c-the-power-of-support.jpg media(min-width: 992px) /> img roleimg src/images/home-slider/cm-the-power-of-support.jpg altThe Power of Support video. /> /picture> div classreal-patient-stories__image-overlay>/div> /div> div classreal-patient-stories__cta> h2 classh3>The Power of Support/h2> a classcta-btn cta-btn--min-width cta-btn-secondary-inverted href/patient-videos/power-of-support>Watch story/a> /div> /div> /li> li classsplide__slide > div classreal-patient-stories__slide story-2> div classreal-patient-stories__image-container> picture> source srcset/images/home-slider/c-self-advocating.jpg media(min-width: 992px) /> img roleimg src/images/home-slider/cm-self-advocating.jpg altSelf-Advocating video. /> /picture> div classreal-patient-stories__image-overlay>/div> /div> div classreal-patient-stories__cta> h2 classh3>Self-Advocating/h2> a classcta-btn cta-btn--min-width cta-btn-secondary-inverted href/patient-videos/self-advocating>Watch story/a> /div> /div> /li> li classsplide__slide > div classreal-patient-stories__slide story-3> div classreal-patient-stories__image-container> picture> source srcset/images/home-slider/c-journey-to-access.jpg media(min-width: 992px) /> img roleimg src/images/home-slider/cm-journey-to-access.jpg altJourney to Access video. /> /picture> div classreal-patient-stories__image-overlay>/div> /div> div classreal-patient-stories__cta> h2 classh3>Journey to Access/h2> a classcta-btn cta-btn--min-width cta-btn-secondary-inverted href/patient-videos/journey-to-access>Watch story/a> /div> /div> /li> li classsplide__slide > div classreal-patient-stories__slide story-4> div classreal-patient-stories__image-container> picture> source srcset/images/home-slider/c-advice.jpg media(min-width: 992px) /> img roleimg src/images/home-slider/cm-advice.jpg altAdvice video. /> /picture> div classreal-patient-stories__image-overlay>/div> /div> div classreal-patient-stories__cta> h2 classh3>Advice/h2> a classcta-btn cta-btn--min-width cta-btn-secondary-inverted href/patient-videos/advice>Watch story/a> /div> /div> /li> li classsplide__slide > div classreal-patient-stories__slide story-5> div classreal-patient-stories__image-container> picture> source srcset/images/home-slider/c-treatment.jpg media(min-width: 992px) /> img roleimg src/images/home-slider/cm-treatment.jpg altTreatment video. /> /picture> div classreal-patient-stories__image-overlay>/div> /div> div classreal-patient-stories__cta> h2 classh3>Treatment/h2> a classcta-btn cta-btn--min-width cta-btn-secondary-inverted href/patient-videos/treatment>Watch story/a> /div> /div> /li> /ul> div classsplide__arrows> button classsplide__arrow splide__arrow--prev> img src/images/arrow-left-yellow.svg alt> /button> button classsplide__arrow splide__arrow--next> img src/images/arrow-right-yellow.svg alt> /button> /div> /div> /article> div classbtn-wrapper> a classcta-btn cta-btn-secondary href/patient-videos>Watch their stories/a> /div>/section>section classshare-your-story with-grid> div classrounded-pearl-container share-your-story__inner-container with-grid> div classcell-1> img classshare-your-story__icon src/images/icon-share-your-story.svg alt> /div> div classcell-2> h2 classshare-your-story__title h1>Share your story/h2> p classshare-your-story__copy h3>You have the chance to make a difference and inspire others. Sharing your XTANDI story can have a positive impact on men living with advanced prostate cancer. To learn more about joining our Ambassador network, give us a call or email today./p> p classshare-your-story__info h3>Call us at a hreftel:844-482-6810 classlink-normal share-your-story__tel inline-link>844-482-6810/a>/p> p classshare-your-story__info h3>Email us at a hrefmailto:amalia@mypatientstory.com classlink-normal share-your-story__mail inline-link>amalia@mypatientstory.com/a>/p> /div> /div>/section>section classselect-safety-information with-grid> h2>Select Safety Information/h2> p> strong>XTANDI may cause serious side effects, including seizure./strong> If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure. a classinline-link href/side-effects>Learn more/a> /p>/section>section classhighlight-container-2 with-grid> div classhighlight-container-2__inner-container with-grid highlight-container-2--borderColorYellow> div classcell-1> img classhighlight-container-2__icon src/images/icon-email.svg alt> h2 classh1>Sign up forbr> support emailsbr> and resources/h2> /div> div classcell-2> p classhighlight-container-2__info h3>We’re here for you with tools, tips, information, and support./p> a href/support-sign-up classcta-btn cta-btn--min-width cta-btn-secondary>Sign up/a> /div> /div>/section>div classcall-1 with-grid> div classcall-1__inner-container with-grid> div classcell-1> p classcall-1__info ts-page-intro-paragraph>For more information on Financial Support, please call a hreftel:1-855-898-2634 classlink-normal call-1__tel phone-link>1-855-898-2634/a>/p> /div> div classcell-2> img classcall-1__icon src/images/icon-ringing-phone.svg alt> a hreftel:1-855-898-2634 classcta-btn cta-btn-secondary-inverted>Call now/a> /div> /div>/div> /main> section idisiPanel classisi> header classisi__header> h2 classisi__header-title>Important Safety Information & Use/h2> button classisi__toggle-btn aria-expandedfalse aria-controlsisiPanel data-isi-toggletrue> span classisi__toggle-btn-label collapsed-only>Find out more/span> span classisi__toggle-btn-label expanded-only>Collapse/span> i classisi__toggle-btn-icon> svg idb xmlnshttp://www.w3.org/2000/svg viewBox0 0 16 16>g idc>g idd>path dm0,8l1.41,1.41L7,3.83v12.17h2V3.83l5.58,5.59,1.42-1.42L8,0,0,8Z fillcurrentColor/>/g>/g>/svg> /i> /button> /header> article classisi__content with-grid> div classcell-1> h2 classts-isi-headline>What should I tell my doctor before taking XTANDI?/h2> p classts-isi-sub-headline>Tell your doctor about all your medical conditions, including if you:/p> ul> li>Have a history of seizures, brain injury, stroke, or brain tumors./li> li>Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia)./li> li>Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage)./li> li>Have a partner who is pregnant or may become pregnant. ul> li>Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose./li> li>Males must use a condom during sex with a pregnant female./li> /ul> /li> li>Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk./li> li>strong>Take other medicines./strong> XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor./li> /ul> /div> div classcell-2> h2 classts-isi-headline>How should I take XTANDI?/h2> ul> li>strong>Take XTANDI exactly as your doctor tells you./strong> Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed./li> li>Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first./li> li>If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration)./li> li>strong>If you miss a dose of XTANDI:/strong> Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day./li> li>strong>If you take too much XTANDI:/strong> Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI./li> /ul> /div> div classcell-3> h2 classts-isi-headline>What are the possible side effects of XTANDI?/h2> p classts-isi-sub-headline>XTANDI may cause serious side effects including:/p> ul> li>strong>Seizure./strong> If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure./li> li>strong>Posterior Reversible Encephalopathy Syndrome (PRES)./strong> If you take XTANDI you may be at risk of developing a condition involving the brain called PRES. Tell your doctor right away if you have a seizure or quickly worsening symptoms such as headache, decreased alertness, confusion, reduced eyesight, blurred vision or other visual problems. Your doctor will do a test to check for PRES./li> li>strong>Allergic Reactions./strong> Allergic reactions have happened in people who take XTANDI. Stop taking XTANDI and get medical help right away if you develop swelling of the face, tongue, lip or throat./li> li>strong>Heart Disease./strong> Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment. Call your doctor or go to the emergency room right away if you get chest pain or discomfort at rest or with activity or shortness of breath during your treatment with XTANDI./li> li>strong>Falls and Bone Fractures./strong> XTANDI treatment may increase your risk for falls and bone fractures. Falls were not caused by loss of consciousness or seizures. Your doctor will monitor your risks for falls and bone fractures during treatment with XTANDI./li> /ul> p>Your doctor will stop treatment with XTANDI if you have serious side effects./p> /div> div classcell-4> h2 classts-isi-sub-headline>The most common side effects of XTANDI include:/h2> ul> li>Muscle and joint pain/li> li>Feeling more tired than usual/li> li>Hot flashes/li> li>Constipation/li> li>Decreased appetite/li> li>Diarrhea/li> li>High blood pressure/li> li>Bleeding problems/li> li>Falls/li> li>Bone fractures/li> li>Headache/li> /ul> p>XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility./p> p>These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist./p> p>strong>Call your doctor for medical advice about side effects. You may report side effects to the FDA at a hreftel:1-800-332-1088 classlink-inherit-styles phone-link>1-800-FDA-1088/a> or a href# classisi-text-link-red wt-open-modal data-bs-togglemodal data-bs-target#popUp2 data-urlhttps://www.fda.gov/medwatch data-labelwww.fda.gov/medwatch>www.fda.gov/medwatch/a>./strong>/p> p>strong>For further information, please talk to your doctor and click here for a classisi-text-link-red hrefhttps://www.astellas.us/docs/us/12A005-ENZ-Patient%20Package%20Insert-WPI.pdf target_blank>Patient Information/a> and a classisi-text-link-red hrefhttps://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf target_blank>Full Prescribing Information/a> for XTANDI./strong>/p> /div> div classcell-5> h2 classts-isi-headline>What is XTANDI?/h2> p>XTANDI is a prescription medicine used to treat men with prostate cancer that:/p> ul> li>no longer responds to a hormone therapy or surgical treatment to lower testosteronebr>OR/li> li>has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosteronebr>OR/li> li>has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body./li> /ul> p>It is not known if XTANDI is safe and effective in females or children./p> /div> /article>/section> footer classfooter> div classfooter__inner-container with-grid> div classcell-1> ul classpage-list> li classpage-list__item> a href/talking-to-your-doctor classpage-list__item-link> div classpage-list__item-cell-1> i classpage-list__item-icon>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-doctor-discussion-guide>/use>/svg>/i> /div> div classpage-list__item-cell-2> h4>Doctor discussion guide/h4> p>A helpful guide for having a productive conversation with your doctor./p> /div> /a> /li> li classpage-list__item> a href/support-sign-up classpage-list__item-link> div classpage-list__item-cell-1> i classpage-list__item-icon>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-sign-up-for-support>/use>/svg>/i> /div> div classpage-list__item-cell-2> h4>Sign up for support/h4> p>Educational materials delivered right to your inbox./p> /div> /a> /li> li classpage-list__item> a href/clinical-trials classpage-list__item-link> div classpage-list__item-cell-1> i classpage-list__item-icon>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-clinical-results>/use>/svg>/i> /div> div classpage-list__item-cell-2> h4>Clinical results/h4> p>Learn more about how XTANDI treats 4 types of advanced prostate cancer./p> /div> /a> /li> li classpage-list__item> a href/financial-support classpage-list__item-link> div classpage-list__item-cell-1> i classpage-list__item-icon>svg viewBox0 0 80 80 aria-hiddentrue focusablefalse>use xlink:href/images/svg-spritesheet-1.svg#icon-sc-financial-support>/use>/svg>/i> /div> div classpage-list__item-cell-2> h4>Financial support/h4> p>See if you’re eligible for financial assistance./p> /div> /a> /li> /ul> /div> div classcell-2> div classcontact> div classcontact__text-container-1> p classcontact__txt-1 footer-paragraph-whitney>This site is intended for U.S. residents onlybr>For information about Access Support call a hreftel:1-855-898-2634 classlink-inherit-styles phone-link text-nowrap>1-855-898-2634/a>/p> /div> div classcontact__text-container-2> p classcontact__txt-2 footer-paragraph-franklin>Call your doctor for medical advice about side effects.br classdesktop> strong>You may report side effects to the FDA at a hreftel:1-800-332-1088 classlink-inherit-styles phone-link text-nowrap>1-800-FDA-1088/a> or a href# classlink-inherit-styles wt-open-modal data-bs-togglemodal data-bs-target#popUp2 data-urlhttps://www.fda.gov/medwatch data-labelwww.fda.gov/medwatch>www.fda.gov/medwatch/a> /strong>/p> /div> /div> div classlogos> a hrefhttps://www.astellas.com/us/ target_blank classlogos__link> img roleimg classlogos__astellas src/images/logo-astellas.png altAstellas Oncology logo.> /a> a hrefhttps://www.pfizer.com/ target_blank classlogos__link> img roleimg classlogos__pfizer src/images/logo-pfizer.png altPfizer Oncology logo.> /a> /div> div classcopyright> p>XTANDI, Astellas, and the flying star logo are registered trademarks of Astellas Pharma Inc./p> p> XTANDI Support Solutionssup classtrademark-reg>®/sup>, a component of Astellas Pharma Support Solutionssup>SM/sup>, is a registered trademark of Astellas Pharma US, span classtext-nowrap>Inc. ©/span> span>2024/span> Astellas Pharma US, Inc. and Pfizer Inc. All Rights Reserved. span classjobcode>076-8908-PM 10/23/span> /p> /div> nav classfooter-nav> ul> li> a href/legal-notice classts-footer-legal-link >Legal Notice/a> /li> li> a href/privacy-statement classts-footer-legal-link >Privacy Statement/a> /li> li> a hrefhttps://www.astellas.com/us/privacy-policy classts-footer-legal-link target"_blank">Privacy Policy/a> /li> li> a href/contact-us classts-footer-legal-link >Contact Us/a> /li> li> a href/sitemap classts-footer-legal-link >Sitemap/a> /li> /ul> /nav> /div> /div>/footer> /div>/body>/html>
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