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AlienVault OTX
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No
DNS Resolutions
Date
IP Address
2019-09-24
52.9.196.166
(
ClassC
)
2024-09-10
104.18.2.134
(
ClassC
)
Port 80
HTTP/1.1 301 Moved PermanentlyDate: Tue, 10 Sep 2024 04:51:42 GMTContent-Type: text/htmlContent-Length: 167Connection: keep-aliveCache-Control: max-age3600Expires: Tue, 10 Sep 2024 05:51:42 GMTLocation: https://www.rituxan.com/Set-Cookie: __cf_bmsfrRi7wXcFR96SXcmwczH2Ac8J.0KujHz8Kbb1LgBRA-1725943902-1.0.1.1-.hWvreI.YbP65c5fzONM3NhbcxiT74l12.tV7zN4xuPhnY84_NBLE2EYg_LdF3lWdZpEH5aAJ_RdhNLKZp8FJw; path/; expiresTue, 10-Sep-24 05:21:42 GMT; domain.rituxan.com; HttpOnlySet-Cookie: __cfruid700f99cfa134722ea1576fd60f451ae365533c4f-1725943902; path/; domain.rituxan.com; HttpOnlySet-Cookie: _cfuvidIo29TSc3qg6wXBE64PBFE2YUn7OU207qLRXTBd.K6G4-1725943902847-0.0.1.1-604800000; path/; domain.rituxan.com; HttpOnlyServer: cloudflareCF-RAY: 8c0ccdf08fca5ed7-PDX html>head>title>301 Moved Permanently/title>/head>body>center>h1>301 Moved Permanently/h1>/center>hr>center>cloudflare/center>/body>/html>
Port 443
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classcmp-hero component-row comp-margin-bottom data-cmp-instance-path/content/rituxan/en_us/index/jcr:content/root/container/hero data-analytics-componenthero data-heading-enabledtrue data-heading-text-shadowNone data-content-visibilityboth> div classpositionable-background cmp-hero__image Left tabindex0 roleimg data-optimg-srcset/content/dam/gene/rituxan/global/desktop/rituxan-patient-desktop-homepage-hero.png, /content/dam/gene/rituxan/global/desktop/rituxan-patient-desktop-homepage-hero.png, > div classcmp-hero__inner cmp-hero__inner--content-center cmp-hero__inner--content-top> div classcmp-hero__content cmp-hero__content--desktop None> h1 classcmp-hero__heading>COMMITTED TO CONNECTING YOU WITH YOUR TREATMENT/h1> div classcmp-hero__content-inner> div classcontainer responsivegrid>div classcmp-container component-row data-cmp-instance-path/content/rituxan/en_us/index/jcr:content/root/container/hero/heroSectionContent/container stylebackground-size:cover;background-repeat:no-repeat; 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href/ra.html target_self data-analytics{\"component\":\"button\",\"destinationTitle\":\"Rheumatoid Arthritis (RA)\",\"location\":\"body\",\"destinationURL\":\"/ra.html\",\"type\":\"internal\"}> i classcmp-button__icon fa fa fa-chevron-right aria-hiddentrue>/i> span classcmp-button__text>Rheumatoid Arthritis (RA) /span> /a>/div>div classbutton>a classcmp-button bttn bttn--primary bttn cmp-button--icon-right skip-analytics data-cmp-instance-path/content/rituxan/en_us/index/jcr:content/root/container/hero/heroSectionContent/container/columncontrol_copy/col-1/button_1129377266 data-analytics-componentbutton data-adobe-analytics-cmp{"btn-d5dce67518":{"destinationTitle":"Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA)","destinationUrl":"/content/rituxan/en_us/gpa-mpa.html","type":"internal","name":"button","key":"btn"}} data-adobe-analytics-idbtn-d5dce67518 href/gpa-mpa.html target_self data-analytics{\"component\":\"button\",\"destinationTitle\":\"Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA)\",\"location\":\"body\",\"destinationURL\":\"/gpa-mpa.html\",\"type\":\"internal\"}> i classcmp-button__icon fa fa fa-chevron-right aria-hiddentrue>/i> span classcmp-button__text>Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA)/span> /a>/div>div classbutton>a classcmp-button bttn bttn--primary bttn cmp-button--icon-right skip-analytics data-cmp-instance-path/content/rituxan/en_us/index/jcr:content/root/container/hero/heroSectionContent/container/columncontrol_copy/col-1/button_1420709869 data-analytics-componentbutton data-adobe-analytics-cmp{"btn-cafe64b32b":{"destinationTitle":"Pemphigus Vulgaris (PV) ","destinationUrl":"/content/rituxan/en_us/pv.html","type":"internal","name":"button","key":"btn"}} data-adobe-analytics-idbtn-cafe64b32b href/pv.html target_self data-analytics{\"component\":\"button\",\"destinationTitle\":\"Pemphigus Vulgaris 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data-author-pathfalse data-inheritance-pathfalse data-analytics-locationsafetybar> div classxf-content-height> div classaem-Grid aem-Grid--12 aem-Grid--default--12 > div classcontainer responsivegrid aem-GridColumn aem-GridColumn--default--12>div idbottom-safety classcmp-container component-row data-cmp-instance-path/content/experience-fragments/gene/rituxan/en_us/patient/safety-information/gateway-safety-bar/jcr:content/root/container stylebackground-size:cover;background-repeat:no-repeat; data-optimg-srcset, , > div classcmp-container__inner content-container > div classsafetybar>section classcmp-safetybar component-row data-cmp-instance-path/content/experience-fragments/gene/rituxan/en_us/patient/safety-information/gateway-safety-bar/jcr:content/root/container/safetybar data-analytics-componentsafetybar data-adobe-analytics-cmp{"isi-da8e4e630a":{"safetyTitle":"Important Side Effect 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two-col_70-30 mobile-stack-right-column-first content-container> div classsafetysnippetlist contentfragmentlist section> div classcmp-safetysnippetlist component-row data-cmp-instance-path/content/experience-fragments/gene/rituxan/en_us/patient/safety-information/gateway-safety-bar/jcr:content/root/container/safetybar/safetybarparsys1/safetysnippetlist data-analytics-componentsafetysnippet> div classcmp-safetysnippetlist__snippets cmp-safetysnippetlist__snippets--first> div classcmp-safetysnippetlist__item idPAT_01Indication> div classcmp-safetysnippetlist__item-richtext> h3>INDICATIONS/h3>div>b>RITUXANsup>®/sup> (rituximab) is a prescription medicine used to treat:/b>/div>ul>li>Adults with Non-Hodgkin’s Lymphoma (NHL): alone or with other chemotherapy medicines./li>li>Children 6 months of age and older with mature B-cell Non-Hodgkin’s Lymphoma (NHL) and mature B-cell acute leukemia (B-AL): in combination with chemotherapy medicines./li>li>Adults with Chronic Lymphocytic Leukemia (CLL): with the chemotherapy medicines fludarabine and cyclophosphamide./li>li>Adults with Rheumatoid arthritis (RA): with another prescription medicine called methotrexate, to reduce the signs and symptoms of moderate to severe active RA, after treatment with at least one other medicine called a tumor necrosis factor (TNF) antagonist has been used and did not work well enough./li>li>People with Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis) and Microscopic Polyangiitis (MPA) ages 2 years and above: with glucocorticoids./li>li>Adults with Pemphigus Vulgaris (PV): to treat moderate to severe PV./li>/ul>p>b>RITUXAN is not indicated in children less than 2 years of age with GPA or MPA or in children less than 6 months of age with mature B-cell NHL and B-AL, or in children with conditions other than GPA, MPA, B-cell NHL and BAL./b>/p> /div> /div> /div> div classcmp-safetysnippetlist__snippets cmp-safetysnippetlist__snippets--remaining> div classcmp-safetysnippetlist__item idPAT_02ImportantSideEffectInformation> div classcmp-safetysnippetlist__item-richtext> h2>b stylefont-size: 16.0px;>What is the most important information I should know about RITUXAN?/b>br />/h2>p>b>RITUXAN can cause serious side effects that can lead to death, including:/b>/p>ul>li>p>b>u>Infusion-Related Reactions:/u>/b> Infusion-related reactions are very common side effects of RITUXAN treatment. Serious infusion-related reactions can happen during your infusion or within 24 hours after your infusion of RITUXAN. Your healthcare provider should give you medicines before your infusion of RITUXAN to decrease your chance of having a severe infusion-related reaction./p>p>Tell your healthcare provider or get medical help right away if you get any of these symptoms during or after an infusion of RITUXAN:/p>ul>li>Hives (red itchy welts) or rash/li>li>Itching/li>li>Swelling of your lips, tongue, throat, or face/li>li>Sudden cough/li>li>Shortness of breath, difficulty breathing, or wheezing/li>li>Weakness/li>li>Dizziness or feel faint/li>li>Palpitations (feel like your heart is racing or fluttering)/li>li>Chest pain/li>/ul>/li>li>b>u>Severe Skin and Mouth Reactions:/u>/b> Tell your healthcare provider or get medical help right away if you get any of these symptoms at any time during your treatment with RITUXAN:ul>li>Painful sores or ulcers on your skin, lips, or in your mouth/li>li>Blisters/li>li>Peeling skin/li>li>Rash/li>li>Pustules/li>/ul>/li>/ul>ul>li>p>b>u>Hepatitis B Virus (HBV) Reactivation:/u>/b> Before you receive your RITUXAN treatment, your healthcare provider will do blood tests to check for HBV infection. If you have had hepatitis B or are a carrier of hepatitis B virus, receiving RITUXAN could cause the virus to become an active infection again. Hepatitis B reactivation may cause serious liver problems, including liver failure, and death. Your healthcare provider will monitor you for hepatitis B infection during and for several months after you stop receiving RITUXAN./p>p>Tell your healthcare provider right away if you get worsening tiredness, or yellowing of your skin or white part of your eyes during treatment with RITUXAN/p>/li>/ul>ul>li>p>u>b>Progressive Multifocal Leukoencephalopathy (PML):/b>/u> PML is a rare, serious brain infection caused by a virus that can happen in people who receive RITUXAN. People with weakened immune systems can get PML. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML./p>p>Tell your healthcare provider right away if you have new or worsening symptoms or if anyone close to you notices these symptoms:/p>ul>li>Confusion/li>li>Dizziness or loss of balance/li>li>Difficulty walking or talking/li>li>Decreased strength or weakness on one side of your body/li>li>Vision problems, such as blurred vision or loss of vision/li>/ul>/li>/ul> /div> /div> div classcmp-safetysnippetlist__item idPAT_03WhatshouldItellmyhealthcareproviderbeforereceivingRITUXAN> div classcmp-safetysnippetlist__item-richtext> p>b>What should I tell my healthcare provider before receiving RITUXAN?/b>/p>p>Before receiving RITUXAN, tell your healthcare provider if you:/p>ul>li>Have had a severe reaction to RITUXAN or a rituximab product/li>li>Have a history of heart problems, irregular heartbeat, or chest pain/li>li>Have lung or kidney problems/li>li>Have had an infection, currently have an infection, or have a weakened immune system/li>li>Have or have had any severe infections including:ul>li>Hepatitis B virus (HBV)/li>li>Hepatitis C virus (HCV)/li>li>Cytomegalovirus (CMV)/li>li>Herpes simplex virus (HSV)/li>li>Parvovirus B19/li>li>Varicella zoster virus (chickenpox or shingles)/li>li>West Nile Virus/li>/ul>/li>li>Have had a recent vaccination or are scheduled to receive vaccinations. You should not receive certain vaccines before or during treatment with RITUXAN/li>li>Have any other medical conditions/li>li>Are pregnant or plan to become pregnant. Talk to your healthcare provider about the risks to your unborn baby if you receive RITUXAN during pregnancy. b>Females who are able to become pregnant: /b>Your healthcare provider should do a pregnancy test to see if you are pregnant before starting RITUXAN and you should use effective birth control (contraception) during treatment with RITUXAN and for 12 months after the last dose of RITUXAN. Talk to your healthcare provider about effective birth control. Tell your healthcare provider right away if you become pregnant or think that you are pregnant during treatment with RITUXAN/li>li>Are breastfeeding or plan to breastfeed. RITUXAN may pass into your breast milk. Do not breastfeed during treatment and for 6 months after your last dose of RITUXAN/li>li>Are taking any medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take or have taken:ul>li>a tumor necrosis factor (TNF) inhibitor medicine/li>li>a disease modifying anti-rheumatic drug (DMARD)/li>/ul>/li>/ul> /div> /div> div classcmp-safetysnippetlist__item idPAT_04WhatarethepossiblesideeffectsofRITUXAN> div classcmp-safetysnippetlist__item-richtext> p>b>What are the possible side effects of RITUXAN?/b>/p>p>RITUXAN can cause serious side effects, including:/p>ul> li>p>b>Tumor Lysis Syndrome (TLS):/b> TLS is caused by the fast breakdown of cancer cells. TLS can cause you to have:/p>ul> li>Kidney failure and the need for dialysis treatment/li> li>Abnormal heart rhythm/li> /ul> p>TLS can happen within 12 to 24 hours after an infusion of RITUXAN. Your healthcare provider may do blood tests to check you for TLS. Your healthcare provider may give you medicine to help prevent TLS./p> p>Tell your healthcare provider right away if you have any of the following signs or symptoms of TLS:/p>ul> li>Nausea/li> li>Vomiting/li> li>Diarrhea/li> li>Lack of energy/li> /ul> /li> li>b>Serious Infections:/b> Serious infections can happen during and after treatment with RITUXAN, and can lead to death. RITUXAN can increase your risk of getting infections and can lower the ability of your immune system to fight infections. Types of serious infections that can happen with RITUXAN include bacterial, fungal, and viral infections. After receiving RITUXAN, some people have developed low levels of certain antibodies in their blood for a long period of time (longer than 11 months). Some of these patients with low antibody levels developed infections. People with serious infections should not receive RITUXAN. Tell your healthcare provider right away if you have any symptoms of infection:ul> li>Fever/li> li>Cold symptoms, such as runny nose or sore throat that do not go away/li> li>Flu symptoms, such as cough, tiredness, and body aches/li> li>Earache or headache/li> li>Pain during urination/li> li>Cold sores in the mouth or throat/li> li>Cuts, scrapes, or incisions that are red, warm, swollen, or painful/li> /ul> /li> li>b>Heart Problems:/b> RITUXAN may cause chest pain, irregular heartbeats, and heart attack. Your healthcare provider may monitor your heart during and after treatment with RITUXAN if you have symptoms of heart problems or have a history of heart problems. Tell your healthcare provider right away if you have chest pain or irregular heart-beats during treatment with RITUXAN/li> li>b>Kidney Problems:/b> especially if you are receiving RITUXAN for NHL. RITUXAN can cause severe kidney problems that lead to death. Your healthcare provider should do blood tests to check how well your kidneys are working/li> li>b>Stomach and Serious Bowel Problems That Can Sometimes Lead to Death:/b> Bowel problems, including blockage or tears in the bowel can happen if you receive RITUXAN with chemotherapy medicines. Tell your healthcare provider right away if you have any stomach-area (abdomen) pain or repeated vomiting during treatment with RITUXAN/li>/ul>p>b>Your healthcare provider will stop treatment with RITUXAN if you have severe, serious, or life-threatening side effects./b>/p> /div> /div> div classcmp-safetysnippetlist__item idPAT_05WhatarethemostcommonsideeffectsduringtreatmentwithRITUXAN> div classcmp-safetysnippetlist__item-richtext> p>b>What are the most common side effects during treatment with RITUXAN?/b>/p>ul>li>infusion-related reactions/li>li>infections (may include fever, chills)/li>li>body aches/li>li>tiredness/li>li>nausea/li>/ul>p>In adults with GPA or MPA, the most common side effects of Rituxan also include:/p>ul>li>low white and red blood cells/li>li>swelling/li>li>diarrhea/li>li>muscle spasms/li>/ul>p>In children with B-cell NHL or B-AL who receive RITUXAN with chemotherapy, the most common side effects include:/p>ul>li>decreased white blood cells with fever/li>li>mouth sores/li>li>inflammation of the upper intestine/li>li>serious infection throughout the body and organs (sepsis)/li>li>changes in liver function blood tests/li>li>low level of potassium in the blood/li>/ul>p>Other side effects include:/p>ul>li>aching joints during or within hours of receiving an infusion/li>li>more frequent upper respiratory tract infections/li>/ul>p>These are not all of the possible side effects with RITUXAN./p>ul>/ul> /div> /div> div classcmp-safetysnippetlist__item idPAT_06Callyourhealthcareprovider> div classcmp-safetysnippetlist__item-richtext> p>b>Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at (800) FDA‐1088 ora hrefhttps://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program target_blank data-analytics{\"component\":\"safetysnippet\",\"destinationTitle\":\"www.fda.gov/medwatch\",\"location\":\"safetybar\",\"destinationURL\":\"https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program\",\"type\":\"external\"} data-adobe-analytics-idlnk-047ed5623a data-adobe-analytics-cmp{"lnk-047ed5623a":{"destinationTitle":"www.fda.gov/medwatch","name":"link","location":"safetybar","destinationURL":"https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program","type":"external","key":"lnk"}}> www.fda.gov/medwatch/a>. You may also report side effects to Genentech at (888) 835‐2555./b>/p>ul>/ul> /div> /div> div classcmp-safetysnippetlist__item idPAT_07PleaseseetheRituxan> div classcmp-safetysnippetlist__item-richtext> p>b>Please see the Rituxan a hrefhttps://www.gene.com/download/pdf/rituxan_prescribing.pdf target_blank data-analytics{\"component\":\"safetysnippet\",\"destinationTitle\":\"Prescribing Information\",\"location\":\"safetybar\",\"destinationURL\":\"https://www.gene.com/download/pdf/rituxan_prescribing.pdf\",\"type\":\"external\"} data-adobe-analytics-idlnk-26d8622a7c data-adobe-analytics-cmp{"lnk-26d8622a7c":{"destinationTitle":"Prescribing Information","name":"link","location":"safetybar","destinationURL":"https://www.gene.com/download/pdf/rituxan_prescribing.pdf","type":"external","key":"lnk"}}>Prescribing Information/a> and a hrefhttps://www.gene.com/download/pdf/rituxan_medguide.pdf target_blank data-analytics{\"component\":\"safetysnippet\",\"destinationTitle\":\"Medication Guide\",\"location\":\"safetybar\",\"destinationURL\":\"https://www.gene.com/download/pdf/rituxan_medguide.pdf\",\"type\":\"external\"} data-adobe-analytics-idlnk-2ac5765dd5 data-adobe-analytics-cmp{"lnk-2ac5765dd5":{"destinationTitle":"Medication Guide","name":"link","location":"safetybar","destinationURL":"https://www.gene.com/download/pdf/rituxan_medguide.pdf","type":"external","key":"lnk"}}>Medication Guide/a> including Most Serious Side Effects for additional Important Side Effect Information./b>br />/p>ul>/ul> /div> /div> /div>/div>/div> /div> div classcmp-safetybar__fade-container>/div> /div> /div> /div> /div>/section>/div> /div>/div>/div> /div>/div>/div> /div>div classexperiencefragment aem-GridColumn aem-GridColumn--default--12> div classcmp-experiencefragment data-cmp-instance-path/conf/rituxan/settings/wcm/templates/flexible-page/structure/jcr:content/root/experiencefragment_1441556533 data-analytics-componentexperiencefragment data-author-pathfalse data-inheritance-pathfalse data-analytics-locationfooter> div classxf-content-height> div classaem-Grid aem-Grid--12 aem-Grid--default--12 > div classcontainer responsivegrid aem-GridColumn aem-GridColumn--default--12>div classcmp-container component-row data-cmp-instance-path/content/experience-fragments/gene/rituxan/en_us/patient/footer/gateway-master/jcr:content/root/container stylebackground-size:cover;background-repeat:no-repeat; 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